Urticaria pigmentosa
Urticaria pigmentosa forma herî gelemperî ya mastosîtoza çerm e. Ew nexweşiyek hindik e ku ji ber hejmareke zêde ya mastxaneyên di çerm de çêdibe ku dema ku aciz dibin li ser çerm birîn an birîn çêdikin. Xalên sor an qehweyî bi gelemperî li ser çerm, bi gelemperî li dora sîng, eniyê û piştê têne dîtin. Van xaneyên mast, dema ku aciz bibin (mînak bi şuştina çerm, rûbirûbûna germê), pir zêde hîstamîn çêdikin, reaksiyonek alerjîk derdixe holê ku dibe sedema mêşên ku li devera acizbûnê ye, ku carinan wekî "nîşana Darier" tê binav kirin.
☆ Di encamên 2022-an de Stiftung Warentest ji Almanyayê, razîbûna xerîdar bi ModelDerm tenê ji şêwirmendên telemedicine drav hindik hindiktir bû.
References
Mastocytosis rewşek e ku tê de zêde hucreyên mast hene, ku pir caran di beşên cûda yên laş de mîna çerm, mêjûya hestî û pergala digestive tê dîtin. Li gorî Rêxistina Tenduristiyê ya Cîhanê (WHO) , cutaneous mastocytosis dikare li sê celebên sereke were categorîzekirin. Tîpa yekem (mastocytomas) ji birînên bitenê an çend (≤3) pêk tê. Cureya duyemîn (urticaria pigmentosa) birînên pirjimar vedihewîne, bi gelemperî ji 10-an zêdetir heya 100-an kêmtir in. Cureya paşîn tevlêbûna berfireh li seranserê çerm nîşan dide. Urticaria pigmentosa forma herî gelemperî ya mastosîtoza çerm di zarokan de ye, lê ew dikare di mezinan de jî çêbibe. Ew bi gelemperî rewşek bê zirar e ku pir caran di dema xortaniyê de baştir dibe. Berevajî mastosîtoza mezinan, urticaria pigmentosa kêm kêm bandorê li organên hundur dike. Taybetmendiyek diyarker a urticaria pigmentosa meyla wê ye ku dibe sedema lekeyên piçûk, xiş, sor-qehweyî, an zer-qehweyî an birînên li ser çerm, ku bi gelemperî wekî mêşok têne zanîn. Van deqan bi gelemperî di zaroktiyê de xuya dibin û dikarin di tevahiya jiyanê de bimînin.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Keçek 6-salî bi çend lekeyên rengên tarî ve hat hundur ku pêşî li ser serê wê xuya bûn û piştre li ser rû û laşê wê di şeş mehên borî de belav bûn. Wê behs kir ku dema ku zext tê kirin hest dikin ku ew radibin, sor dibin, û xiş dibin. Wê tecrubeya sorbûn, vereşîn, îshal, an xişandinê nebû, û dîroka wê ya bijîjkî ya kesane û malbatî îşaretên têkildar peyda nekir. Li ser muayeneyê, me li ser serê wê, eniya, rû û stûyê wê, li gel deqên tarî yên hinekî bilindkirî li ser sîng û pişta wê, gelek deqên tarî dîtin. Bi sivikî xişandina deqan di nav 2 hûrdeman de biwerimîn û xiş kirin, lê nîşanên di nav 15-20 hûrdeman de winda bûn (Darier's sign) .
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
